salmonella typhimurium (ta100) mutagenicity of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5h)-furanone and its open- and closed-ring analogs
β Scribed by Robert T. Lalonde; Gary P. Cook; Hannu Perakyla; Carlton W. Dence; John G. Babish; J. H. Carver
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 818 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0893-6692
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π SIMILAR VOLUMES
The chlorinated drinking water mutagen 3-chloro-4-methyl-5-hydroxy-2(5H)-furanone (MCF) occurs at concentrations similar to or greater than that of the related furanone 3-chloro-4-(dichloromethyl)-5hydroxy-2(5H)-furanone (MX). MCF and MX differ structurally only by replacement of a 3-methyl in MCF w
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract 3βChloroβ4β(dichloromethyl)β5βhydroxyβ2(5__H__)βfuranone (MX) is a genotoxic chlorination byβproduct in drinking water. There is some evidence that it has developmental toxic effects in vitro but its potential to cause developmental effects in vivo is not known. The developmental effect