Induction of gastrointestinal tract nuclear anomalies in b6c3f1 mice by 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5h]-furanone and 3,4-(dichloro)-5-hydroxy-2[5h]-furanone, mutagenic byproducts of chlorine disinfection
β Scribed by F. B. Daniel; J. A. Stober; G. R. Olson; S. M. Galloway
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 802 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0893-6692
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The frequency of point mutations in p53 (exons 4 -7) and in Ki-ras, Ha-ras, and N-ras (exons 1 and 2) and the expression of p53 protein were evaluated in the liver tumors of Wistar rats of a 104week carcinogenicity study on 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX), a chlorine disinf
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