Townsend, S.E., and S.N. Sehgal: Mutagenicity evaluation of tetrahydro-amino acridine by the Salmonella/microsome mutagenicity Ames test. Drug Dev. Res. 14:91-94, 1988. 1,2,3,4-tetrahydr0-5-amino acridine (THA), a cholinesterase inhibitor currently under investigation for use in the treatment of sen
Salmonella mutagenicity tests: IV. Results from the testing of 300 chemicals
β Scribed by Errol Zeiger; Beth Anderson; Steve Haworth; Timothy Lawlor; Kristien Mortelmans
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 849 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0893-6692
No coin nor oath required. For personal study only.
β¦ Synopsis
Three hundred chemicals were tested for mutagenicity, under code, in Salmonella typhimurium, using a preincubation protocol. All tests were performed in the absence of exogenous metabolic activation, and in the presence of liver S-9 from Aroclor-induced male Sprague-Dawley rats and Syrian hamsters. The results and data from these tests are presented.
π SIMILAR VOLUMES
Twenty-five laser dyes and four analogs were tested for mutagenicity in the Amesl Salmonella test. Seven dyes and two analogs gave positive mutagenic responses with bacterial strains TA1538 and TA98. Of two widely used families of laser dyes (coumarins and rhodamines), four coumarin samples, but non