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Salivary α-amylase exhibits antiproliferative effects in primary cell cultures of rat mammary epithelial cells and human breast cancer cells

✍ Scribed by Maren Fedrowitz; Ralf Hass; Catharina Bertram; Wolfgang Löscher


Book ID
115025398
Publisher
BioMed Central
Year
2011
Tongue
English
Weight
525 KB
Volume
30
Category
Article
ISSN
1756-9966

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We examined the effects of 1alpha,25-dihydroxycholecalciferol (1,25-DHCC) and the glucocorticoid, cortisol, on primary mouse mammary epithelial cells in collagen gel cell culture systems. Physiological low concentrations (10(-11)-10(-9) M) of 1,25-DHCC stimulated growth of the cells in a collagen ge