Salivary Acetaldehyde Concentration According to Alcoholic Beverage Consumed and Aldehyde Dehydrogenase-2 Genotype
β Scribed by Akira Yokoyama; Eri Tsutsumi; Hiromi Imazeki; Yoshihide Suwa; Chizu Nakamura; Takeshi Mizukami; Tetsuji Yokoyama
- Book ID
- 109124116
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 259 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0145-6008
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π SIMILAR VOLUMES
## Abstract The lessβactive homozygous alcohol dehydrogenaseβ1B (__ADH1B\*1/\*1__) and inactive heterozygous aldehyde dehydrogenaseβ2 (__ALDH2\*1/\*2__) increase the risk of upper aerodigestive tract cancer (UADTC) in Japanese alcoholics. We evaluated associations between ADH1B/ALDH2 genotypes and
In this study, 1,000 Japanese male alcoholics were consecutively screened by upper gastrointestinal endoscopy with esophageal iodine staining. Associations among cancer-detection rates, drinking and smoking habits, and aldehyde dehydrogenase-2 (ALDH2) genotypes were evaluated. A total of 53 patients