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Polymorphisms of Alcohol Dehydrogenase-1B and Aldehyde Dehydrogenase-2 and the Blood and Salivary Ethanol and Acetaldehyde Concentrations of Japanese Alcoholic Men

✍ Scribed by Akira Yokoyama; Eri Tsutsumi; Hiromi Imazeki; Yoshihide Suwa; Chizu Nakamura; Tetsuji Yokoyama

Book ID
109124564
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
267 KB
Volume
34
Category
Article
ISSN
0145-6008

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✍ Akira Yokoyama; Eri Tsutsumi; Hiromi Imazeki; Yoshihide Suwa; Chizu Nakamura; Te πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 French βš– 141 KB

## Abstract The less‐active homozygous alcohol dehydrogenase‐1B (__ADH1B\*1/\*1__) and inactive heterozygous aldehyde dehydrogenase‐2 (__ALDH2\*1/\*2__) increase the risk of upper aerodigestive tract cancer (UADTC) in Japanese alcoholics. We evaluated associations between ADH1B/ALDH2 genotypes and