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Safety and tolerance of sorafenib in Japanese patients with advanced hepatocellular carcinoma

✍ Scribed by Sadahisa Ogasawara; Fumihiko Kanai; Shuntaro Obi; Shinpei Sato; Taketo Yamaguchi; Ryosaku Azemoto; Hideaki Mizumoto; Youhei Koushima; Naoki Morimoto; Nobuto Hirata; Takeshi Toriyabe; Yusuke Shinozaki; Yoshihiko Ooka; Rintaro Mikata; Tetsuhiro Chiba; Shinichiro Okabe; Fumio Imazeki; Masaharu Yoshikawa; Osamu Yokosuka

Book ID: 107593940
Publisher: Springer-Verlag
Year: 2011
Tongue: English
Weight: 182 KB
Volume: 5
Category: Article
ISSN: 1936-0533
DOI: 10.1007/s12072-010-9249-4

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The team of Liu et al. generated endoderm-derived human induced pluripotent stem (iPS) cells from primary hepatocytes. 1 However, they generated human iPS cells by using viral transgenes. 1 Clinical applications of human iPS cells require avoiding viral transgenes. On the other hand, the reprogrammi