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PR-104 plus sorafenib in patients with advanced hepatocellular carcinoma

✍ Scribed by Ghassan K. Abou-Alfa; Stephan L. Chan; Chia-Chi Lin; E. Gabriela Chiorean; Randall F. Holcombe; Mary F. Mulcahy; William D. Carter; Kashyap Patel; William R. Wilson; Teresa J. Melink; John C. Gutheil; Chao-Jung Tsao

Book ID: 105993718
Publisher: Springer
Year: 2011
Tongue: English
Weight: 180 KB
Volume: 68
Category: Article
ISSN: 0344-5704
DOI: 10.1007/s00280-011-1671-3

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The team of Liu et al. generated endoderm-derived human induced pluripotent stem (iPS) cells from primary hepatocytes. 1 However, they generated human iPS cells by using viral transgenes. 1 Clinical applications of human iPS cells require avoiding viral transgenes. On the other hand, the reprogrammi