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Safety and plasma levels of human recombinant IL-1 receptor antagonist administered by continuous infusion in humans


Book ID
122853245
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
167 KB
Volume
3
Category
Article
ISSN
1043-4666

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Prostaglandins and thromboxanes (Txs) are produced by polymorphonuclears (PMNs) and macrophages (Mphis) in response to various stimuli. PMNs were separated from other human blood cells and Mphis were separated from rat peritoneal lavage. In this paper we show that human recombinant interleukin-1 (hr