## Abstract ## Purpose To assess the safety, effective dose, and efficacy of a novel hepatobiliary MR contrast agent GdβDTPAβDeA for imaging liver tumors, from the clinical phase I and phase II trials in Japan. ## Materials and Methods In a phase I trial, 33 healthy volunteers were intravenously
β¦ LIBER β¦
Safety and Efficacy of a Novel Hepatobiliary MR Contrast Agent GN-1140 (Gd-DTPA-DeA)
β Scribed by Tanimoto, Akihiro; Kadoya, Masumi; Kawamura, Yasutaka; Kuwatsuru, Ryohei; Gokan, Takehiko; Hirohashi, Shinji
- Book ID
- 121912968
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 547 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1076-6332
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## Purpose: To investigate the characteristics of gd-dtpa-dea as a hepatobiliary contrast agent for mr imaging in comparison with those of gd-eob-dtpa. ## Materials and methods: We undertook phantom experiments to assess t1 relaxivity for gd-dtpa-dea, gd-eob-dtpa, and gd-dtpa in human plasma. for