𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Saccharide–RNA recognition

✍ Scribed by Thomas Hermann; Eric Westhof

Book ID
102650991
Publisher
Wiley (John Wiley & Sons)
Year
1998
Tongue
English
Weight
559 KB
Volume
48
Category
Article
ISSN
0006-3525

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✦ Synopsis

Among saccharides, the antibiotics of the aminoglycoside family are the best-studied class of molecules interacting with RNA. By binding to RNA targets, aminoglycosides act as inhibitors of protein biosynthesis, they interfere with protein-RNA interaction of retroviral regulatory elements, and they inhibit the catalytic action of ribozymes. Here, we survey the available data on molecular structural details of aminoglycoside-RNA interaction.

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