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Sa1688 Polyamine and Methionine Adenosyltransferase 2A Crosstalk in Human Colon Cancer

โœ Scribed by Tomasi, Maria Lauda; Ryoo, Minjung; Skay, Anna; Tomasi, Ivan; Giordano, Pasquale; Mato, Jose M.; Lu, Shelly C.

Book ID
122149958
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
122 KB
Volume
144
Category
Article
ISSN
0016-5085

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Leptin's mitogenic effect in human liver
Leptin's mitogenic effect in human liver cancer cells requires induction of both methionine adenosyltransferase 2A and 2ฮฒ
โœ Komal Ramani; Heping Yang; Meng Xia; Ainhoa Iglesias Ara; Josรฉ M. Mato; Shelly C ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 698 KB

Leptin is an adiopokine that plays a pivotal role in the progression of liver fibrogenesis and carcinogenesis. Recently, leptin was shown to be mitogenic in human liver cancer cell lines HepG2 and Huh7. Whether leptin can act as a mitogen in normal hepatocytes is unclear. Methionine adenosyltransfer