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NC2213: a novel methionine aminopeptidase 2 inhibitor in human colon cancer HT29 cells

✍ Scribed by Ponniah Selvakumar; Ashakumary Lakshmikuttyamma; Umashankar Das; Hari N Pati; Jonathan R Dimmock; Rajendra K Sharma


Book ID
119902026
Publisher
BioMed Central
Year
2009
Tongue
English
Weight
780 KB
Volume
8
Category
Article
ISSN
1476-4598

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Our previous study demonstrated that, stanniocalcin-1 (STC1) was a target of histone deacetylase (HDAC) inhibitors and was involved in trichostatin A (TSA) induced apoptosis in the human colon cancer cells, HT29. In this study, we reported that the transcriptional factor, specificity protein 1 (Sp1)