𝔖 Bobbio Scriptorium
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S7.5 The role of CD45 in NK cell recognition and signaling

✍ Scribed by M. Pospîsil; K. Bezouška; A. Fišerová; Ng. H. Huan; G. Trinchieri

Publisher
Springer US
Year
1993
Tongue
English
Weight
132 KB
Volume
10
Category
Article
ISSN
1573-4986

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CD4, CD8 and CD45 regulate the coupling of the T-cell receptor complex (CD3-TCR) to tyrosine kinase activation and phosphorylation of key substrates such as phospholipase C gamma 1. CD4 and CD8 contribute to activation signals through their cytoplasmic association with p56lck. Expression of the zeta