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S.28.05 D-Serine acting at the glycine site of NMDA receptor in psychiatric disorders

โœ Scribed by A. Zimmer; D.M. Otte; M. Barcena de Arellano; I. Racz


Book ID
118598065
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
54 KB
Volume
21
Category
Article
ISSN
0924-977X

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Hypofunction of the N-methyl-D-aspartate receptor (NMDAR) has been implicated in the pathophysiology of schizophrenia. The NMDAR contains a D-serine/glycine site on the NR1 subunit that may be a promising therapeutic target for psychiatric illness. This review outlines the complex regulation of endo