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S1795 Decreased Spontaneous Activity and Excitability of Gallbladder Smooth Muscle in a Mouse Model of Gallstone Disease

✍ Scribed by Balemba, Onesmo B.; Lavoie, Brigitte; Bartoo, Aaron C.; Mawe, Gary M.


Book ID
122498286
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
116 KB
Volume
134
Category
Article
ISSN
0016-5085

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## Abstract Niemann‐Pick disease type C (NPC) is a progressive neurodegenerative disorder characterized by accumulation of free cholesterol in lysosomes, mainly due to a mutation in the NPC1 gene. The pathophysiological basis of the neural disorders in NPC, however, is not well understood. We found