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Accelerated aging of the GABAergic septohippocampal pathway and decreased hippocampal rhythms in a mouse model of Alzheimer's disease

โœ Scribed by Rubio, S. E.; Vega-Flores, G.; Martinez, A.; Bosch, C.; Perez-Mediavilla, A.; del Rio, J.; Gruart, A.; Delgado-Garcia, J. M.; Soriano, E.; Pascual, M.

Book ID
115442323
Publisher
The Federation of American Societies for Experimental Biology
Year
2012
Tongue
English
Weight
603 KB
Volume
26
Category
Article
ISSN
0892-6638

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โœ Michael H. Donovan; Umar Yazdani; Rebekah D. Norris; Dora Games; Dwight C. Germa ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 623 KB

Abnormal subgranular zone (SGZ) neurogenesis is proposed to contribute to Alzheimer's disease (AD)-related decreases in hippocampal function. Our goal was to examine hippocampal neurogenesis in the PDAPP mouse, a model of AD with age-dependent accumulation of amyloid-โค 42 (Aโค 42 )-containing plaques