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S1-04-01: Functional polymorphisms in low-density lipoprotein receptor, brain APOE receptor, and Alzheimer's disease risk

✍ Scribed by Steven Estus

Book ID
118463756
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
72 KB
Volume
4
Category
Article
ISSN
1552-5260

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## Abstract A number of studies suggest that brain cholesterol metabolism may play a role in Alzheimer's disease (AD) development, probably through modulation of amyloid beta production. The discovery that apolipoprotein E (__APOE__) Ξ΅4 allele is a risk factor for sporadic AD raises the possibility