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(S)-reticuline induces vasorelaxation through the blockade of L-type Ca2+channels

✍ Scribed by Marcos Antônio A. Medeiros; Xirley P. Nunes; José M. Barbosa-Filho; Virginia S. Lemos; José F. Pinho; Danilo Roman-Campos; Isac A. de Medeiros; Demetrius Antonio M. Araújo; Jader S. Cruz


Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
408 KB
Volume
379
Category
Article
ISSN
0028-1298

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## Abstract Opioids can induce analgesia and also hyperalgesia in humans and in animals. It has been shown that systemic administration of morphine induced a hyperalgesic response at an extremely low dose. However, the exact mechanism(s) underlying opioid‐induced hyperalgesia has not yet been clari