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S-Nitroso-N-acetyl-DL-penicillamine

✍ Scribed by Carnahan, G. E. ;Lenhert, P. G. ;Ravichandran, R.

Book ID
114525375
Publisher
International Union of Crystallography
Year
1978
Weight
416 KB
Volume
34
Category
Article
ISSN
0567-7408

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πŸ“œ SIMILAR VOLUMES

Chemical mechanisms underlying the vasod
Chemical mechanisms underlying the vasodilator and platelet anti-aggregating properties of S-nitroso-N-acetyl-dl-penicillamine and S-nitrosoglutathione
✍ Stuart C. Askew; Anthony R. Butler; Frederick W. Flitney; Graham D. Kemp; Ian L. πŸ“‚ Article πŸ“… 1995 πŸ› Elsevier Science 🌐 English βš– 686 KB

The chemistries of S-nitroso-DL-penicillamine (SNAP) and S-nitrosoglutathione (GSNO) in relation to their ability to relax vascular smooth muscle and prevent platelet aggregation have been investigated. Metal ion catalysis greatly accelerates the decomposition of SNAP, but has little effect on GSNO.

N-acetyl-DL-penicillamine and acetaminop
N-acetyl-DL-penicillamine and acetaminophen toxicity in mice
✍ Richard T. Zera; Herbert T. Nagasawa πŸ“‚ Article πŸ“… 1980 πŸ› John Wiley and Sons 🌐 English βš– 247 KB

N-Acetyl-DL-penicillamine (IIIb), a structural analog of N-acetyl-L-cysteine (IIIa), did not protect mice from lethal doses of acetaminophen (I), whereas IIIa offered protection. This lack of efficacy of IIIb probably is due to the decreased nucleophilicity of its sulfhydryl group compared to that o