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(S)-homoquisqualate: a potent agonist at the glutamate metabotropic receptor

✍ Scribed by Richard H.P. Porter; Peter J. Roberts; David E. Jane; Jeffrey C. Watkins


Book ID
117959740
Publisher
Nature Publishing Group
Year
1992
Tongue
English
Weight
381 KB
Volume
106
Category
Article
ISSN
0007-1188

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Straightforward stereocontrolled synthesis of (2S)-2-hydroxymethylglutamic acid was achieved from (S)-pyroglutaminol, through a bicyclic silyloxypyrrole derived from the versatile unsaturated lactam 3.