## Abstract Activity of the myelin marker enzyme 2′,3′‐cyclic nucleotide 3′‐phosphohydrolase (CNP) was assayed in cerebrospinal fluid samples obtained from patients with multiple sclerosis (MS) and other neurological diseases. The enzyme activity was found to be elevated in acute cases of MS and re
S-100 protein and 2′,3′-cyclic nucleotide 3′-phosphohydrolase in human brain tumors
✍ Scribed by F. C. Dohan; P. L. Kornblith; G. R. Wellum; S. E. Pfeiffer; L. Levine
- Publisher
- Springer-Verlag
- Year
- 1977
- Tongue
- English
- Weight
- 570 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0001-6322
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The development in primary dissociated rat brain cultures of 2',3'-cyclic nucleotide 3'-phosphohydrolase (CNP) activity, the accumulation of CNP protein, and the number of cells accumulating this protein have been quantitatively determined as a function of time in culture. Parallel determinations ha
In order to investigate the role of the myelin-associated enzyme 2' 3'cyclic nucleotide 3'-phosphohydrolase in the development of the myelin sheath, as well as genetic factors involving dysmyelinating disorders, we have recently isolated and sequenced cDNAs corresponding to the CNPase protein. In th