## Abstract Although several lines of evidence implicate cAMP in the regulation of intestinal cell proliferation, the precise role of this second messenger in the control of the human colon cancer cell cycle is still unclear. In order to investigate the role of cAMP in HT29 cell proliferation, we h
RxFISH karyotype and MYC amplification in the HT-29 colon adenocarcinoma cell line
✍ Scribed by Cristina Corzo; Miriam Petzold; Xavier Mayol; Blanca Espinet; Marta Salido; Sergi Serrano; Francisco X. Real; Francesc Solé
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 78 KB
- Volume
- 36
- Category
- Article
- ISSN
- 1045-2257
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Cell cycle regulation is dependent on multiple cellular and molecular events. Cell proliferation requires metabolic sources for the duplication of DNA and cell size. However, nucleotide reservoirs are not sufficient to support cell duplication and, therefore, biosynthetic pathways shoul
Sulindac sulfide (SS), the active metabolite of the colon cancer chemopreventive compound sulindac, inhibits the proliferation of HT-29 colon cancer cells mainly by inducing cell quiescence. We determined by bivariate flow-cytometric analysis both the DNA and cyclin protein content of individual cel