Ruthenium(II) complexes of optically active P, N donor ligands. Synthesis and evaluation in the catalytic hydrogenation of acetophenone

✍ Scribed by Hong Yang; Noël Lugan; René Mathieu

• Publisher: Elsevier Science
• Year: 1999
• Tongue: English
• Weight: 603 KB
• Volume: 2
• Category: Article
• ISSN: 1387-1609
• DOI: 10.1016/s1387-1609(99)80072-3

✦ Synopsis

The reaction of 2 equiv of the optically active P, N bidentate ligands l-3 with RuC1,(PPh,)3 gives the RuCl,(l-3)2 (4-6) complexes in good yield as a mixture of isomers. The solid state structure of RuC1,( 2), (SC) is described: the two chlorine atoms are in tram position and due to steric crowding, one of the two ligands 2 is more weakly bound to Ru. The complexes 4-6 show moderate to good catalytic activity for the hydrogenation of acetophenone in basic media in hydrogen transfer conditions, from propanol-2, or under dihydrogen, but the enantiomeric excesses are low. 0 Acadtmie des sciences/Elsevier, Paris