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Ruthenium-Catalyzed Synthesis of Indoles from Anilines and Epoxides

✍ Scribed by Peña-López, Miguel; Neumann, Helfried; Beller, Matthias


Book ID
121758437
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
371 KB
Volume
20
Category
Article
ISSN
0947-6539

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Ruthenium-catalyzed synthesis of indoles
✍ Chan Sik Cho; Jin Hwang Kim; Sang Chul Shim 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 157 KB

Anilines react with trialkanolammonium chlorides in an aqueous medium (H 2 O-dioxane) at 180°C in the presence of a catalytic amount of ruthenium(III) chloride hydrate and triphenylphosphine together with tin(II) chloride dihydrate to afford the corresponding indoles in good yields.