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RUNX1mutation associated with clonal evolution in relapsed pediatric acute myeloid leukemia with t(16;21)(p11;q22)

✍ Scribed by Ismael, Olfat; Shimada, Akira; Elmahdi, Shaimaa; Elshazley, Momen; Muramatsu, Hideki; Hama, Asahito; Takahashi, Yoshiyuki; Yamada, Miho; Yamashita, Yuka; Horide, Keizo; Kojima, Seiji

Book ID
125378988
Publisher
Carden Jennings Publishing
Year
2013
Tongue
English
Weight
336 KB
Volume
99
Category
Article
ISSN
0925-5710

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## Abstract The t(1;21)(p36;q22) is a recurrent chromosome abnormality associated with therapy‐related acute myeloid leukemia (AML). Although involvement of __RUNX1__ has been detected by fluorescence in situ hybridization analysis, the partner gene has not been reported previously. We identified a