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Rubitecan: beneficial effects in advanced pancreatic adenocarcinoma

Book ID
120864234
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2001
Weight
149 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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Phase II study of amonafide in advanced
Phase II study of amonafide in advanced pancreatic adenocarcinoma
โœ Kaye Linke; Richard Pazdur; James L. Abbruzzese; Jaffer A. Ajani; Rodger Winn; J ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer US ๐ŸŒ English โš– 262 KB

To determine the efficacy of amonafide in patients with advanced, measurable pancreatic adenocarcinoma, 15 patients previously untreated with chemotherapy were entered on a phase II trial. The starting dose was 400 mg/m 2 administered daily over 1 hr for 5 consecutive days repeated every 3 weeks. Be