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Phase II trial of edatrexate in patients with advanced pancreatic adenocarcinoma

✍ Scribed by Ephraim S. Casper; Gary K. Schwartz; Bruce Johnson; David P. Kelsen


Publisher
Springer US
Year
1992
Tongue
English
Weight
293 KB
Volume
10
Category
Article
ISSN
0167-6997

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Phase II study of amonafide in advanced
✍ Kaye Linke; Richard Pazdur; James L. Abbruzzese; Jaffer A. Ajani; Rodger Winn; J πŸ“‚ Article πŸ“… 1991 πŸ› Springer US 🌐 English βš– 262 KB

To determine the efficacy of amonafide in patients with advanced, measurable pancreatic adenocarcinoma, 15 patients previously untreated with chemotherapy were entered on a phase II trial. The starting dose was 400 mg/m 2 administered daily over 1 hr for 5 consecutive days repeated every 3 weeks. Be