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RT-PCR Increases Detection of Submicroscopic Peritoneal Metastases in Gastric Cancer and Has Prognostic Significance

✍ Scribed by Wong, Joyce ;Kelly, Kaitlyn J. ;Mittra, Arjun ;Gonen, Mithat ;Allen, Peter J. ;Fong, Yuman ;Coit, Daniel G.


Book ID
122301079
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
423 KB
Volume
140
Category
Article
ISSN
0016-5085

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Detection of free cancer cells in the peritoneal cavity by RT-PCR using carcinoembryonic antigen (CEA) as a target gene is a more sensitive predictor of peritoneal dissemination than conventional cytology in gastric-cancer patients. Difficulties with this method are the lack of quantitative assessme