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RT-PCR Increases Detection of Submicroscopic Peritoneal Metastases in Gastric Cancer and Has Prognostic Significance

✍ Scribed by Joyce Wong; Kaitlyn Jane Kelly; Arjun Mittra; Mithat Gonen; Peter Allen; Yuman Fong; Daniel Coit

Book ID: 113086156
Publisher: Springer-Verlag
Year: 2012
Tongue: English
Weight: 259 KB
Volume: 16
Category: Article
ISSN: 1091-255X
DOI: 10.1007/s11605-012-1845-2

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Detection of free cancer cells in the peritoneal cavity by RT-PCR using carcinoembryonic antigen (CEA) as a target gene is a more sensitive predictor of peritoneal dissemination than conventional cytology in gastric-cancer patients. Difficulties with this method are the lack of quantitative assessme