(R,R)-2,5-Diphenylpyrrolidine: Diastereoselective Radical Addition to the Derived Methacrylamide
β Scribed by Douglass F Taber; Gregory J Gorski; Louise M Liable-Sands; Arnold L Rheingold
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 251 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
Rsdicat additionof thiophenolto the methacryhrnide1 with high disstereoseketivity, to give 2 and 3 in a ratio of 25:1. 0 Elsevier Science
π SIMILAR VOLUMES
Tertiary amines derived from pyrrolidines can be added veD' efficiently (isolated yields up to 94%) to (SR)-5-mentyloxy-2[5H]-furanone. The addition, which follows a radical chain mechanism initiated by a photoinitiated electron transfer (PET) from the tertiary amine to the excited aromatic ketone,
Highly diastereoselective nucleophilic addition reactions of organometallic reagents to formyl[2.2]paracyclophane derivatives which were ortho-substituted by hydroxy-, alkoxy-and trimethylsilyloxy-groups are reported. The absolute configuration of the newly formed secondary alcohols is assigned on t