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Rottlerin inhibits multiple steps involved in insulin-induced glucose uptake in 3T3-L1 adipocytes

✍ Scribed by Merlijn Bazuine; Gerard C.M van der Zon; Rob van de Ven; Peter J.A van den Broek; J Antonie Maassen


Book ID
113487139
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
251 KB
Volume
68
Category
Article
ISSN
0006-2952

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Nigericin inhibits insulin-stimulated gl
✍ Chih-Ying Chu; Ying-Shun Kao; Jim C. Fong πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 187 KB

## Abstract We used nigericin, a K^+^/H^+^ exchanger, to test whether glucose transport in 3T3‐L1 adipocytes was modulated by changes in intracellular pH. Our results showed that nigericin increased basal but decreased insulin‐stimulated glucose uptake in a time‐ and dose‐dependent manner. Whereas