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Rotigotine transdermal patch in moderate to severe idiopathic restless legs syndrome: A randomized, placebo-controlled polysomnographic study

✍ Scribed by Wolfgang H. Oertel; Heike Beneš; Diego Garcia-Borreguero; Birgit Högl; Werner Poewe; Pasquale Montagna; Luigi Ferini-Strambi; Friederike Sixel-Döring; Claudia Trenkwalder; Markku Partinen; Bernd Saletu; Olli Polo; Andreas Fichtner; Erwin Schollmayer; Ralf Kohnen; Werner Cassel; Thomas Penzel; Karin Stiasny-Kolster

Book ID: 119368078
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 363 KB
Volume: 11
Category: Article
ISSN: 1389-9457
DOI: 10.1016/j.sleep.2010.02.014

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## Abstract Efficacy and safety of the dopamine agonist rotigotine (RTG) was investigated in patients with moderate to severe idiopathic restless legs syndrome (RLS), including daytime symptoms. Three fixed doses of rotigotine (1.125 mg, 2.25 mg, and 4.5 mg) and placebo were applied by patches (siz