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Efficacy of rotigotine for treatment of moderate-to-severe restless legs syndrome: a randomised, double-blind, placebo-controlled trial

✍ Scribed by Claudia Trenkwalder; Heike Beneš; Werner Poewe; Wolfgang H Oertel; Diego Garcia-Borreguero; Al W de Weerd; Luigi Ferini-Strambi; Pasquale Montagna; Per Odin; Karin Stiasny-Kolster; Birgit Högl; K Ray Chaudhuri; Markku Partinen; Erwin Schollmayer; Ralf Kohnen


Book ID
114408935
Publisher
The Lancet
Year
2008
Tongue
English
Weight
213 KB
Volume
7
Category
Article
ISSN
1474-4465

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## Abstract Efficacy and safety of the dopamine agonist rotigotine (RTG) was investigated in patients with moderate to severe idiopathic restless legs syndrome (RLS), including daytime symptoms. Three fixed doses of rotigotine (1.125 mg, 2.25 mg, and 4.5 mg) and placebo were applied by patches (siz