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Rothmund-Thomson Syndrome in Fraternal Twins

✍ Scribed by Melinda Tong


Book ID
115308913
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
147 KB
Volume
12
Category
Article
ISSN
0736-8046

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The Rothmund-Thomson syndrome (RTS), also called poikiloderma congenitale is a rare autosomal recessive disease first described in 1868. This syndrome includes most frequently seen skin lesions (atrophy, telangiectases, pigmentation), cataracts and bone defects (dysostosis, dysplasia). Some authors

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Two children who had the Rothmund-whom information was available showed un-Thomson syndrome and developed osteo-due sensitivity to cancer chemotherapy agents sarcoma are reported. The 10 previously re-with prolonged myelosuppression and severe ported cases are reviewed. The osteosarco-mucositis. It