𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Osteogenic sarcoma in the Rothmund-Thomson syndrome

✍ Scribed by Leonard, Andrea; Craft, Alan W.; Moss, Celia; Malcolm, Archie J.


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
377 KB
Volume
26
Category
Article
ISSN
0098-1532

No coin nor oath required. For personal study only.

✦ Synopsis


Two children who had the Rothmund-whom information was available showed un-Thomson syndrome and developed osteo-due sensitivity to cancer chemotherapy agents sarcoma are reported. The 10 previously re-with prolonged myelosuppression and severe ported cases are reviewed. The osteosarco-mucositis. It is recommended that doxorubimas developed at a younger age than cin in particular should be given with extreme normally expected and 66% occurred in the caution in such patients.


πŸ“œ SIMILAR VOLUMES


Growth hormone deficiency in the Rothmun
✍ Kaufmann, Silvia ;Jones, Marilyn ;Culler, Floyd L. ;Jones, Kenneth Lee ;Opitz, J πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 English βš– 516 KB

We describe the first proven Occurrence of growth hormone deficiency in an individual with the Rothmund-Thomson syndrome. This was suspected because of the patient's severely retarded growth and bone age and her failure to respond normally to growth hormone stimulation testing with I-DOPA, arginine,

Clonal lines of aneuploid cells in Rothm
✍ Der Kaloustian, Vazken M. ;McGill, James J. ;Vekemans, Michel ;Kopelman, Hinda R πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 399 KB

We report on a 21-month-old white boy with the Rothmund-Thomson syndrome. The karyotype on fibroblasts from an area of skin with poikiloderma showed the 46,XY,17 + der(17),t(2;17)(qll;p13) pattern. ## Karyotype on fibroblasts from normal skin showed two different abnormal patterns: 47,XY, + 8 and

Chromosomal instability in fibroblasts a
✍ Monica Miozzo; Pierangela Castorina; Paola Riva; Leda DalprΓ ; Anna Maria Fuhrman πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 French βš– 383 KB

Rothmund-Thomson syndrome (RTS) is a rare autosomal recessive genodermatosis associated with increased risk of mesenchymal tumors. The putative gene has been provisionally assigned to chromosome 8. Using a cytogenetic-molecular approach, we studied lymphocytes, fibroblasts, osteosarcoma (OS) and mal

Osteogenic sarcoma in the American black
✍ Andrew G. Huvos; Avital Butler; Sara S. Bretsky πŸ“‚ Article πŸ“… 1983 πŸ› John Wiley and Sons 🌐 English βš– 665 KB