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Roots: The discovery (or rediscovery?) of the phenomenon of premature chromosome condensation

✍ Scribed by Potu N. Rao

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
661 KB
Volume
12
Category
Article
ISSN
0265-9247

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Mitotic CHO cells and mouse testicular cells were fused with polyethylene glycol. Several types of prematurely condensed chromosomes were observed. From chromosome morphology it was possible to determine that most of the PCC represented mouse cells. Labeling of either the CHO cells in vitro or the t

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## Abstract The object of this study was to develop a map of G1 phase on the basis of the progressive changes taking place in the morphology of the prematurely condensed chromosomes as the cells traverse through G1 and then use this technique to determine the cell cycle location of normal and trans

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## Abstract The objective of this study was to determine the points in the cell cycle at which normal and transformed cells become arrested as a result of polyamine deprivation. Treatment of normal (human fibroblast line PA2 and mouse 3T3) and transformed (CHO, HeLa and SV3T3) cells with methylglyo