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Room Temperature Palladium-Catalyzed Cross Coupling of Aryltrimethylammonium Triflates with Aryl Grignard Reagents

✍ Scribed by Reeves, Jonathan T.; Fandrick, Daniel R.; Tan, Zhulin; Song, Jinhua J.; Lee, Heewon; Yee, Nathan K.; Senanayake, Chris H.

Book ID
118147691
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
448 KB
Volume
12
Category
Article
ISSN
1523-7060

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AbstractÐAryl tri¯ates may be cross-coupled with the amino acid derived zinc reagents 1, 2 and 3 using palladium catalysis at room temperature, in the presence of anhydrous lithium chloride, conveniently yielding phenylalanine 4, b-homophenylalanine 5 and g-bishomophenylalanine 6 derivatives respect