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Room Temperature Palladium-Catalysed Coupling of Amino Acid-Derived Organozinc Reagents with Aryl Triflates

✍ Scribed by Charles S Dexter; Richard F.W Jackson; Jason Elliott


Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
63 KB
Volume
56
Category
Article
ISSN
0040-4020

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✦ Synopsis


AbstractÐAryl tri¯ates may be cross-coupled with the amino acid derived zinc reagents 1, 2 and 3 using palladium catalysis at room temperature, in the presence of anhydrous lithium chloride, conveniently yielding phenylalanine 4, b-homophenylalanine 5 and g-bishomophenylalanine 6 derivatives respectively (nine examples).


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