Room Temperature Palladium-Catalysed Coupling of Amino Acid-Derived Organozinc Reagents with Aryl Triflates
β Scribed by Charles S Dexter; Richard F.W Jackson; Jason Elliott
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 63 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0040-4020
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β¦ Synopsis
AbstractΓAryl triΒ―ates may be cross-coupled with the amino acid derived zinc reagents 1, 2 and 3 using palladium catalysis at room temperature, in the presence of anhydrous lithium chloride, conveniently yielding phenylalanine 4, b-homophenylalanine 5 and g-bishomophenylalanine 6 derivatives respectively (nine examples).
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