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Room Temperature Ionic Liquids Promoted Three-Component Coupling Reactions: A Facile Synthesis of cis-Isoquinolonic Acids.

✍ Scribed by J. S. Yadav; B. V. S. Reddy; K. Saritha Raj; A. R. Prasad


Publisher
John Wiley and Sons
Year
2003
Weight
165 KB
Volume
34
Category
Article
ISSN
0931-7597

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## Abstract magnified image A mild and stereoselective three‐component one‐step synthesis of __cis__‐isoquinolonic acid using silica sulfuric acid as a heterogeneous catalyst from an aldehyde, amine and homophthalic anhydride in acetonitrile is described. This new method produces pure products in