Romping the cellular landscape: linear scaffolds for molecular recognition
β Scribed by Younjoo Lee; Nicole S Sampson
- Book ID
- 113883091
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 724 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0959-440X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The triamino steroid 2 is synthesized from cholic acid (1), and found to possess little tendency to aggregate at pH 5 -6 in aqueous solution. 2 and/or related derivatives are expected to find use in the synthesis of receptors and combinatorial libraries, and as "contrafacial amphiphiles" for drug de
Energy landscapes of molecular recognition are explored by performing "semi-rigid" docking of FK-506 and rapamycin with the Fukisawa binding protein (FKBP-121, and flexible docking simulations of the Ro-31-8959 and AG-1284 inhibitors with HIV-1 protease by a genetic algorithm. The requirements of a