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Roles of thymidylate synthase and dihydropyrimidine dehydrogenase expression in blood as predictors of response to multimodal therapy in esophageal cancer

✍ Scribed by Jan Brabender; Ralf Metzger; Daniel Vallböhmer; Frederike Ling; Susanne Neiss; Elfriede Bollschweiler; Paul M. Schneider; Arnulf H. Hölscher; Peter P. Grimminger


Book ID
113921828
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
188 KB
Volume
151
Category
Article
ISSN
0039-6060

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Thymidylate synthase and dihydropyrimidi
✍ Wataru Ichikawa; Takehiro Takahashi; Kenichi Suto; Zenro Nihei; Yoshinori Shirot 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 269 KB

## Abstract Thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) are important enzymes of DNA __de novo__ synthesis and the salvage pathway in cancer cells, respectively. Intratumoral TS and DPD gene expressions were evaluated to determine the correlation between the expression of th