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Roles of the NKG2D immunoreceptor and its ligands

✍ Scribed by Raulet, David H.

Book ID
109953915
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
302 KB
Volume
3
Category
Article
ISSN
1474-1741

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## Abstract NKG2D is a receptor expressed by NK cells and subsets of T lymphocytes. On NK cells, NKG2D functions as a stimulatory receptor that induces effector functions. We cloned and expressed two rat NKG2D ligands, both members of the RAE1 family, RAE1L and RRLT, and demonstrate that these liga