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Roles of the LHX3 and LHX4 LIM-homeodomain factors in pituitary development

✍ Scribed by Rachel D. Mullen; Stephanie C. Colvin; Chad S. Hunter; Jesse J. Savage; Emily C. Walvoord; Amrit P.S. Bhangoo; Svetlana Ten; Johannes Weigel; Roland W. Pfäffle; Simon J. Rhodes


Book ID
116734130
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
314 KB
Volume
265-266
Category
Article
ISSN
0303-7207

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## Abstract LHX3 is a LIM homeodomain transcription factor with essential roles in pituitary and motor neuron development in mammals. Patients with mutations in the __LHX3__ gene have combined pituitary hormone deficiency and other symptoms. In this study, we show that the LHX3 protein can be modif