Characterization of the porcine Lhx3/LIM-3/P-Lim LIM homeodomain transcription factor
β Scribed by Bradley C. Meier; Jeffrey R. Price; Gretchen E. Parker; JeAnne L. Bridwell; Simon J. Rhodes
- Book ID
- 117464098
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 325 KB
- Volume
- 147
- Category
- Article
- ISSN
- 0303-7207
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## Abstract LHX3 is a LIM homeodomain transcription factor with essential roles in pituitary and motor neuron development in mammals. Patients with mutations in the __LHX3__ gene have combined pituitary hormone deficiency and other symptoms. In this study, we show that the LHX3 protein can be modif
## Abstract Summary: We cloned and characterized the ISL2 and LHX2 LIMβhomeodomain transcription factors of the Mexican salamander, or axolotl, __Ambystoma mexicanum.__ Using a degenerate PCR approach, partial cDNAs representing five LIMβhomeodomain genes were cloned, indicating conservation of thi