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Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis

✍ Scribed by Goodman, Myron F.; Tang, Mengjia; Pham, Phuong; Shen, Xuan; Taylor, John-Stephen; O'Donnell, Mike; Woodgate, Roger


Book ID
109769385
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
356 KB
Volume
404
Category
Article
ISSN
0028-0836

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✍ Anetta Nowosielska; Celina Janion; Elzbieta Grzesiuk πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 125 KB

The E. coli dnaQ gene encodes the epsilon subunit of DNA polymerase III (pol III) responsible for the proofreading activity of this polymerase. The mutD5 mutant of dnaQ chronically expresses the SOS response and exhibits a mutator phenotype. In this study we have constructed a set of E. coli AB1157