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All three SOS-inducible DNA polymerases (Pol II, Pol IV and Pol V) are involved in induced mutagenesis

✍ Scribed by Napolitano, R.


Book ID
111747665
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
236 KB
Volume
19
Category
Article
ISSN
0261-4189

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The E. coli dnaQ gene encodes the epsilon subunit of DNA polymerase III (pol III) responsible for the proofreading activity of this polymerase. The mutD5 mutant of dnaQ chronically expresses the SOS response and exhibits a mutator phenotype. In this study we have constructed a set of E. coli AB1157