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Roles of calcineurin and calcium/calmodulin-dependent protein kinase II in pressure overload-induced cardiac hypertrophy

✍ Scribed by Tetsuya Saito; Jun Fukuzawa; Junzo Osaki; Hitoshi Sakuragi; Naoyuki Yao; Takashi Haneda; Takayuki Fujino; Nobutaka Wakamiya; Kenjiro Kikuchi; Naoyuki Hasebe

Book ID
117142423
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
422 KB
Volume
35
Category
Article
ISSN
0022-2828

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## Abstract Recent in vitro studies suggest that adenosine monophosphate (AMP)‐activated protein kinase (AMPK) exerts inhibitory effects on cardiac hypertrophy. However, it is unclear whether long‐term activation of AMPK will affect cardiac hypertrophy in vivo. In these reports, we investigate the