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Roles for dysfunctional sphingolipid metabolism in Alzheimer's disease neuropathogenesis

✍ Scribed by Norman J. Haughey; Veera V.R. Bandaru; Mihyun Bae; Mark P. Mattson

Book ID
116273523
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
899 KB
Volume
1801
Category
Article
ISSN
1388-1981

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## Abstract Abnormalities in mitochondrial function relate to the spectrum of pathological changes seen in Alzheimer's disease. Here we review the causes and consequences of mitochondrial disturbances in Alzheimer's disease as well as how this information might impact on therapeutic approaches to t