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Role of γ-glutamyltranspeptidase and β-lyase in the nephrotoxicity of hexachloro-1,3-butadiene and methyl mercury in mice

✍ Scribed by de Ceaurriz, J.; Ban, M.


Book ID
121903944
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
574 KB
Volume
50
Category
Article
ISSN
0378-4274

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Role of extracellular glutathione and γ-
✍ J. De Ceaurriz; J. P. Payan; G. Morel; M. T. Brondeau 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 547 KB

The role of extracellular glutathione (GSH) and membrane-bound y-glutamyltranspeptidase (yGT) as contributory factors in the disposition and toxicity of inorganic mercury (HgCI2, 1 mg kg-', i.p.) was investigated in rats pretreated with acivicin (AT-125, 10 mg kg-I), a y-GT inhibitor. A high degree